PRO20044 nucleic acids

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S069100, C435S358000, C435S252300, C435S252330, C435S254110, C435S254200, C435S320100, C530S350000, C536S023100, C536S023500

Reexamination Certificate

active

07135334

ABSTRACT:
Compositions and methods are disclosed for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals, including humans. Pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be diagnosed, prevented, or treated by the compositions herein include trauma such as wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac hypertrophy. In addition, the present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

REFERENCES:
patent: WO 01/36440 (2001-05-01), None
patent: WO 01/77137 (2001-10-01), None
patent: WO 02/08284 (2002-01-01), None
patent: WO 02/095010 (2002-11-01), None
patent: WO 02/102993 (2002-12-01), None
Skolnick et al. (2000). From genes to protein structure and function: novel applications of computational approaches in the genomic era. Trends in Biotech. 18(1):34-39.
Bork, A. (2000). Powers and pitfalls in sequence analysis: the 70% hurdle. Genome Res. 10:398-400.
Doerks et al. (1998). Protein annotation: detective work for function prediction. Trends in Genetics. 14(6):248-250.
Smith et al. (1997). The challenges of genome sequence annotation or The devil is in the details. Nature Biotech. 15:1222-1223.
Brenner, S.E. (1999). Errors in genome function. Trends in Genetics. 15(4):132-133.
Bork et al. (1996). Go hunting in sequence databases but watch out for the traps. Trends in Genetics. 12(10):425-427.
Wells, J.A. (1990). Additivity of mutational effects in proteins. Biochemistry. 29(37):8509-8517.
Ngo et al. (1994). Computational complexity, protein structure prediction, and the Levinthal paradox. In Merz and Le Grand (Eds.) The Protein Folding Problem and Tertiary Structure Prediction. Birkhauser:Boston, pp. 492-495.
Stratagene Product Catalog (1991). PRIME-IT™ Random Primer Labeling Kit, Catalog # 300387.
Accession No. HSDJ144C9(Hall, R.), Creation Date Jul. 2, 1999.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

PRO20044 nucleic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with PRO20044 nucleic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and PRO20044 nucleic acids will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3692624

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.