Primycin-containing colloidal basic gel

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 65, A61K 3170, C07H 1708

Patent

active

050648152

ABSTRACT:
This invention relates to a primycin-containing colloidal basic gel comprising 5-30% of primycin and 95-70% of N-methyl-pyrrolidone-2. The invention also relates to antibacterial compositions particularly for the treatment of acne vulgaris comprising as active ingredient 0.1-100% of a primycin-containing colloidal basic gel, if desired together with further antimicrobial active ingredients, in admixture with 99.9-0% of usual inert pharmaceutical filling, diluting and other formulating additives. The invention also relates to combination composition comprising as active ingredient 1-60% of a primycin-containing colloidal basic gel and 0.1-40% of further pharmaceutical active ingredient(s), e.g. one or more antibiotic(s), chemotherapeutical agent(s), fungistatic or fungicidal agent(s), steroidal or non-steroidal antiinflammatory agent (s), epithelogenic agent(s), local anaesthetic(s), and/or vitamin(s).

REFERENCES:
patent: 4132781 (1979-01-01), Stoughton
patent: 4268498 (1981-09-01), Gedeon et al.
patent: 4537776 (1985-08-01), Cooper
patent: 4557934 (1985-12-01), Cooper
Merck Index, 10th Ed., Compound 7652.
The Condensed Chemical Dictionary, 10th Ed., Hawley, pp. 97 and 1127 (1981).

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