Preparation of quinoline-substituted carbonate and carbamate...

Details Preparation of quinoline-substituted carbonate and carbamate... Preparation of quinoline-substituted carbonate and carbamate...

2006-07-11

2006-07-11

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S167000, C546S180000

Reexamination Certificate

active

07074932

ABSTRACT:
The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

REFERENCES:
patent: 4154834 (1979-05-01), Brown et al.
patent: 6417366 (2002-07-01), Allen et al.
patent: 6437106 (2002-08-01), Stoner et al.
patent: 6455680 (2002-09-01), Lukin
patent: 6579986 (2003-06-01), Allen et al.

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