Preparation of physostigmine carbamate derivatives from physosti

Details Preparation of physostigmine carbamate derivatives from physosti Preparation of physostigmine carbamate derivatives from physosti

1994-03-22

1996-03-12

Haley, Jacqueline

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D48700

Patent

active

054987261

ABSTRACT:
This application relates to a new process for the preparation of a product of the formula ##STR1## wherein R, R.sup.1, R.sup.2, X and m are as defined within, which process comprises preparing treating a compound such as physostigmine to form eseroline which is then treated with an appropriate compound or its equivalent. Acetic acid is added to the reaction mixture after the formation of eseroline.

REFERENCES:
patent: 4900748 (1990-02-01), Brossi et al.
patent: 4914102 (1990-04-01), Glamkowski
patent: 4978673 (1990-12-01), Meroni et al.
patent: 5077289 (1991-12-01), Glamkowski et al.

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