Preparation of opiates, intermediates and uses of salts

Details Preparation of opiates, intermediates and uses of salts Preparation of opiates, intermediates and uses of salts

1998-06-30

2000-07-18

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 45, C07D47108

Patent

active

060909439

ABSTRACT:
A process for the preparation of thebaine, its salts such as the bitartrate, and analogues thereof, together with a novel intermediate useful in said process are disclosed. Thebaine bitartrate is itself useful in the preparation of oxycodone; analogues are useful in the preparation of analogous 14-hydroxymorphinones.

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"Houben Weyl: Methoden der Organischen Chemie, Bd. E15", (1993), George Thieme Verlag, Stuttgart, pp. 201-205 (XP002078245).

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