Preparation of hydroxy aromatic carboxylic acids and ester deriv

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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562406, 562467, 562475, 568737, 568774, 568779, 560 67, C07C 6994

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active

043742629

ABSTRACT:
A process for preparing hydroxy aromatic carboxylic acids, or the ester derivatives thereof, comprises carbonylating a hydroxy aromatic halide in the presence of a reactive alcohol solvent and a catalytic amount of a Group VIII metal catalyst. The process has particular applicability to the preparation of 6-hydroxy-2-naphthoic acid from 6-bromo-2-naphthol, which can be easily prepared from .beta.-naphthol, a readily available and inexpensive starting material.

REFERENCES:
patent: 3700729 (1972-10-01), Fenton
patent: 3717670 (1973-02-01), Schultz
Falbe, J., "Carbon Monoxide in Organic Synthesis", pp. 118-120, Springer-Verlag, 1970.

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