Sulfonamides as antifungal agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5482672, A01N 43653, C07D24908

Patent

active

053608135

ABSTRACT:
The present invention relates to new sulfonamides having the formula I: ##STR1## wherein: R.sup.1 represents an alkyl, aryl or heteroaryl group; R.sup.2 is hydrogen or an alkyl, aryl or heteroaryl group; or R.sup.1 and R.sup.2 may form a ring; R.sup.3 is hydrogen or may form an oxazolidine ring together with R.sup.2, and this ring may be optionally substituted by one or two alkyl, aryl or heteroaryl groups at the postion 2; R.sup.7 is hydrogen or alkyl; X is CH or N; Ar is a phenyl ring or a substituted phenyl ring. The invention also relates to a procedure for their preparation and to pharmaceutical and agrochemical compositions containing them. These compounds are antifungal agents.

REFERENCES:
Konosu et al, "Triazole Antifungals. IV. Synthesis, etc" Chem. Pharm. Bull 39 (10) 2581-2589 (1991).

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