Preparation methods of diterpene lactone compounds and applicati

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514841, 549297, A61K 3134, C07D30777

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active

054300541

ABSTRACT:
The invention provides methods of preparing a male antifertility agent composed of a diterpene lactone compound obtained from plants of the genus Tripterygium, the diterpene lactone compounds obtained from that method, and the use of the compounds as an antifertility agent.

REFERENCES:
Shao-Zhen Qian et al., Contraception 33(2):105-110 (Feb. 1986).
Shao Zhen Qian et al., Contraception 36(3):335-345 (Sep. 1987).
Deng Fu-Xiao et al., Acta Botanica Sinica 27:316-519 (1985) [English translation of paragraphs related to triptolidenol].
S. Morris Kupchan et al., J. Amer. Chem. Soc. 94:20, pp. 7194-7195 (Oct. 1972).

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