Precursors to radiopharmaceutical agents for tissue imaging

Details Precursors to radiopharmaceutical agents for tissue imaging Precursors to radiopharmaceutical agents for tissue imaging

1987-03-13

1988-08-16

Terapane, John F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Diazoamino

546316, 424 11, C07C11500, C09B 5620

Patent

active

047645989

ABSTRACT:
A class of radiolabeled compounds to be used in tissue imaging that exhibits rapid brain uptake, good brain:blood radioactivity ratios, and long retention times. The imaging agents are more specifically radioiodinated aromatic amines attached to dihydropyridine carriers, that exhibit heart as well as brain specificity. In addition to the radiolabeled compounds, classes of compounds are also described that are used as precursors and intermediates in the preparation of the imaging agents.

REFERENCES:
patent: 3162571 (1964-12-01), Adams et al.
patent: 3741951 (1973-06-01), Hess et al.
patent: 4479932 (1984-10-01), Bodor
patent: 4514408 (1985-04-01), Nisato et al.
Tedjamulia, M. L. et al, "Brain-Specific Delivery of Radioiodinated Amine J. Med. Chem., Nov. 1985, pp. 1574-1580.

Affiliated with

Also associated with

Rating

Precursors to radiopharmaceutical agents for tissue imaging does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Precursors to radiopharmaceutical agents for tissue imaging, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Precursors to radiopharmaceutical agents for tissue imaging will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-601288