Radiant energy – Photocells; circuits and apparatus – Photocell controls its own optical systems
Reexamination Certificate
2006-10-31
2006-10-31
Le, Que T. (Department: 2878)
Radiant energy
Photocells; circuits and apparatus
Photocell controls its own optical systems
C250S208100
Reexamination Certificate
active
07129454
ABSTRACT:
A Precision Optical Intracellular Near Field Imaging/Spectroscopy Technology (POINT/NANOPOINT) is a high-resolution instrument for analyzing and comparing molecular characteristics of cells. A nanosensor array is provided which is capable of imaging inner regions of living cells without destroying its natural environment and providing new information about molecular makeup of cells. The POINT probe collects data from high-resolution imagery, providing an imaging tool for investigating cells at sub-cellular and molecular levels. Data are then incorporated into a signature facilitating molecular analysis of diseases. The POINT probe non-invasively penetrates cell membranes to image insides of intact cells allowing the POINT probe to collect data without destroying cell structures. The probe provides cellular imaging to enable the viewing of both imaging and spectroscopy of internal regions of cells. The POINT system may be attached to existing microscopes to achieve a very high resolution.
REFERENCES:
patent: 5004307 (1991-04-01), Kino et al.
patent: 5939709 (1999-08-01), Ghislain et al.
patent: 6208886 (2001-03-01), Alfano et al.
patent: 6775009 (2004-08-01), Hill
patent: 6818907 (2004-11-01), Stark
patent: 2003/0215844 (2003-11-01), Chapsky et al.
Tang et al.;Consideration and control of writing conditions with a near-field APSIL probe; Proceedings of International Symposium on Optical Memory and Optical Data Storage/2002; ISBN 0-7803-7379-0; Published:2002; pp. 243-245.
Tom D. Milster et al.;Super-Resolution by Combination of a Solid Immersion lens and Aperture; The Japan Society of Applied Physics, Part 1, No. 3B; Mar. 2001.
Bert Hecht et al.;Scanning near-field optical microscopy with aperture probes; Fundamentals and applications; Special Topic: Near-Field Microscopy and Spectroscopy; Journal of Chemical Physics, vol. 112, No. 18; May 8, 2000.
Eric Betzig and Robert J. Chichester;Single Molecules Observed by Near-Field Scanning Optical Microscopy; Science, New Series, vol. 262, No. 5138; Nov. 26, 1993; pp. 1422-1425.
S.M. Mansfield and G. S. Kino;Solid Immersion Microscope; Appl. Phys. Lett., vol. 57, No. 24; Dec. 10, 1990.
O'Connell Dan
O'Connell-Rodwell Caitlin
Creighton Wray James
Le Que T.
Nanopoint, Inc.
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