Porphyrin-polyamine conjugates for cancer therapy

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S185000, C424S009362, C424S009610, C540S145000, C534S015000

Reexamination Certificate

active

07026347

ABSTRACT:
Porphyrin-polyamine conjugate compounds are disclosed which have anticancer and antitumor effects. The porphyrin moiety selectively localizes in tumors, while the polyamine moiety serves as a cytotoxic agent. Methods of making and using the porphyrin-polyamine conjugate compounds are also disclosed.

REFERENCES:
patent: 4443604 (1984-04-01), Lee
patent: 4784736 (1988-11-01), Lonsdale et al.
patent: 5275801 (1994-01-01), Niedballa et al.
patent: 5912341 (1999-06-01), Hoffman et al.
patent: 6114321 (2000-09-01), Platzek et al.
patent: 6207660 (2001-03-01), Sessler et al.
patent: 6395257 (2002-05-01), Achilefu et al.
patent: 6906050 (2005-06-01), Robinson
patent: 2002/0155999 (2002-10-01), Han
patent: 2003/0036538 (2003-02-01), Rajagopalan et al.
patent: 2003/0100752 (2003-05-01), Robinson
patent: 2004/0192665 (2004-09-01), Frydman et al.
patent: WO 00/66587 (2000-11-01), None
patent: WO 200066587 (2000-11-01), None
patent: WO-02/10142 (2002-02-01), None
patent: WO-03/004091 (2003-01-01), None
patent: WO-03/004091 (2003-01-01), None
patent: WO-03/004466 (2003-01-01), None
patent: WO-03/004466 (2003-01-01), None
patent: WO-03/051348 (2003-06-01), None
patent: WO-2004/002991 (2004-01-01), None
patent: WO-2004/012774 (2004-02-01), None
patent: WO-2004/041828 (2004-05-01), None
Ando, A. et al. (Aug. 1990). “Synthesis of Fluorine Analogues of Protoporphyrin Potentially Useful for Diagnosis and Therapy of Tumors,”Chemical and Pharmaceutical Bulletin38(8):2175-2178.
Brunner, H. et al. (1994). “Platinum(II) Complexes With Porphyrin Ligands—Additive Cytotoxic and Photodynamic Effect,”Angew. Chem. Int. Ed. Engl, 33(21):2214-2215.
Kramer, D.L. et al. (Dec. 15, 1997). “Effects of Novel Spermine Analogues on Cell Cycle Progression and Apoptosis in MALME-3M Human Melanoma Cells,”Cancer Research57:5521-5527.
Sharma, A. et al. (Aug. 1997). “Antitumor Efficacy of N1, N11-Diethylnorspermine on a Human Bladder Tumor Xenograft in Nude Athymic Mice,”Clinical Cancer Research3:1239-1244.
Stemberg, E. et al. (Aug. 1996), “Pyrrolic Photosensitizers,”Current Medicinal Chemistry3(4):239-272.
Wamser, C.C. et al. (1989), “Thin-Film Composite Membranes for Artificial Photosynthesis. Final Report, July 15, 1985-Mar. 31, 1989,”National Technical Information Service, 41 pages.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Porphyrin-polyamine conjugates for cancer therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Porphyrin-polyamine conjugates for cancer therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Porphyrin-polyamine conjugates for cancer therapy will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3611760

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.