Polypeptide derivatives and calcium metabolism improving agent

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530307, 530317, A61K 3702, C07K 512, C07K 736

Patent

active

052043266

ABSTRACT:
Novel polypeptide derivatives, acid-addition salts thereof and complexes thereof, having the activities for inhibiting bone calcium absorption, for lowering the blood level of calcium, as analgesics, for inhibiting secretion of the gastric juice.
Pharmaceutical composition can be prepared by formulating, at least one of the novel polypeptide derivatives, acid-addition salts thereof and complexes thereof, together with a proteolytic enzyme inhibitors and/or pharmaceutically acceptable acids.
The pharmaceutical composition are quite effective as agents for curing hypercalcemia, for curing Peget's disease, for curing osteoporosis, analgetic agent, anti-ulcerative agent and the like.

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