Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Patent
1999-06-10
2000-07-25
Zitomer, Stephanie W.
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
422 681, 422101, 422 8205, 435 6, 4352872, 4352884, 4352887, G01N 3300, C12Q 168
Patent
active
060933704
ABSTRACT:
Different probes each having a specific base sequence are immobilized to each of independent areas formed on the surface of a substrate, complementary polynucleotides in a sample solution are hybridized to the probes, and each of the independent areas on the substrate is heated and then cooled in sequence, and hence the solution is recovered to extract different polynucleotides separately corresponding to individual probes.
REFERENCES:
patent: 4446237 (1984-05-01), Berninger
patent: 4893886 (1990-01-01), Ashkin et al.
patent: 5605662 (1997-02-01), Heller et al.
patent: 5607646 (1997-03-01), Heller et al.
"Space-Resolved Control of Protein Subunit Dissociation/Association Using Laser Heating", '94, Aug. 1994, M. Washizu et al, pp. 111-114.
"Scanning Tunneling Microscopy of Mercapto-Hexyl-Oligonucleotides Attached to Gold", Biophysical Journal, vol. 71, Aug. 1996, D. Rekesh et al, pp. 1079-1086.
"Electrostatic Manipulation of Bioparticles", Kona, No. 14, M. Washizu, pp. 61-71.
"Light-Directed, Spatially Addressable Parallel Chemical Synthesis", Science, vol. 251, Feb. 15, 1991, Fodor et al, pp. 767-773.
"Remote Thermal Imaging With 0.7--um Spatial Resolution Using Temperature-Dependent Fluorescent Thin Films", Applied Physical Letters, 42(1), Jan. 1, 1983, P. Kolodner et al pp. 117-119.
"Covalent Attachment of Hybridizable Oligonucleotides to Glass Supports", Analytical Biochemistry, vol. 247, 1997, B. Joos et al, pp. 96-101.
"Covalent Immobilization of DNA onto Polystyrene Microwells: The Molecules Are Only Bound at the 5 'End", Analytical Chemistry, 198, 1991, S. Rasmussen et al, pp. 138-142.
"DNA Analysis and Diagnostics on Oligonucleotide Microchips", Proceedings National Academy of Science USA, 93, 1996, G. Yershov et al.
Kato Hirokazu
Okano Kazunori
Yasuda Kenji
Hitachi , Ltd.
Zitomer Stephanie W.
LandOfFree
Polynucleotide separation method and apparatus therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polynucleotide separation method and apparatus therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polynucleotide separation method and apparatus therefor will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1334518