Polynucleotide associated with breast cancer comprising...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S091100, C536S023100, C536S024300

Reexamination Certificate

active

07833710

ABSTRACT:
Provided is a polynucleotide for diagnosis or treatment of breast cancer, including at least 10 contiguous nucleotides of a nucleotide sequence selected from the group consisting of nucleotide sequences of SEQ ID No: 1 to SEQ ID No: 5 and comprising a nucleotide at 101stposition of the nucleotide sequence, or a complementary polynucleotide thereof.

REFERENCES:
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patent: 9605306 (1996-02-01), None
patent: 01/77384 (2001-10-01), None
patent: 2004028346 (2004-04-01), None
Cox et al; 2006; Breast Cancer Research, vol. 9, No. 1, pp. 1-5.
Hegele Arterioscler. Thromb. Vasc. Biol.; 2002, vol. 22, pp. 156-1061.
Lucentini The Scientist; 2004, vol. 24, p. 20.
Horner et al; “Breast Cancer Rates by Age” SEER Cancer Statistics Review, 1975-2006; NCI 2008.
Ren, Z., et al.; “Genetic Polymorphisms in the Human Growth Hormone-1 Gene (GH1) and the Risk of Breast Carcinoma”; Cancer; vol. 101, No. 2; pp. 251-257; Jul. 15, 2004.
Kadouri, L., et al.; “A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BCRA1 carriers or noncarriers”; British Journal of Cancer; vol. 90; pp. 2002-2005; 2004.
Tower, G.B., et al.; “The 2G single nucleotide polymorphism (SNP) in the MMP-1 promoter contributes to high levels of MMP-1 transcription in MCF-7/ADR breast cancer cells”; Breast Cancer Research and Treatment; vol. 82; pp. 75-82; 2003.
Mimori, K., et al.; “A Single-Nucleotide Polymorphism of SMARCB1 in Human Breast Cancers”; Genomics; vol. 80, No. 3; pp. 254-258; Sep. 2002.
International Search Report dated May 17, 2006 for Application No. PCT/KR2006/000505 (All references cited in Search Report are listed above).
Written Opinion dated May 17, 2006 for Application No. PCT/KR2006/000505.
Wu and Wallace, Genomics 4, 560 (1989).
Landegren, etc., Science 241, 1077 (1988).
Kwoh, etc., Proc. Natl. Acad. Sci. USA 86, 1173 (1989).
Guatelli, etc., Proc. Natl. Acad. Sci. USA 87, 1874 (1990).
Gusella, Ann. Rev. Biochem. 55. 831-854 (1986).
Nielsen et al., Science 254, 1497-1500 (1991).
J. Sambrook, et al.; “Molecular Cloning: A Laboratory Manual”; Cold Spring Harbor Press, Second Edition, pp. 13.1-13.20, 1989.
EP Extended Search Report; Application No. EP 06715956.6 (EP regional application of PCT/2006000505) dated Jun. 8, 2009.
EPO Communication dated Apr. 11, 2009 citing database documents of accession Nos. ABF99372 and ABF99373.
Kadouri et al., “A single-nucleotide polymorphism in the RAD51 gene modifies breast cancer risk in BRCA2 carriers, but not in BRCA1 carriers or noncarriers,” British Journal of Cancer, 2004, vol. 90, No. 10, pp. 2002-2005.
Mimori, et al. “A Single-Nucleotide Polymorphism of SMARCB1 in Human Breast Cancers,” Genomics, 2002, vol. 80, No. 3, pp. 254-258.
Ren et al., “Genetic Polymorphisms in the Human Growth Hormone-1 Gene (GH1) and the Risk of Breast Carcinoma,” Cancer, 2004, vol. 101, No. 2, pp. 251-257.
Tower et al., “The 2G single nucleotide polymorphism (SNP) in the MMP-1 promoter contributes to high levels of MMP-1 transcription in the MCF-7/ADR breast cancer cells,” Breast Cancer Research and Treatment, 2003, vol. 82, No. 2, pp. 75-82.
XP002526198 “Homo sapienschromosome 19 clone RP11-294120 map 19, working draft sequence,” retrieved from EBI accession No. EMBL: AC023583, (Feb. 16, 2000).
XP002526199 “Homo sapienschromosome 19 clone CTD-3195E18, complete sequence,” retrieved from EBI accession No. EMBL: AC112706, (Feb. 28, 2002).
XP002526200 “Homo sapienschromosome 19 clone X200282, complete sequence,” retrieved from EBI accession No. EMBL: AC092074, (Jun. 20, 2001).

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