Polymorphic forms of sertraline hydrochloride

Details Polymorphic forms of sertraline hydrochloride Polymorphic forms of sertraline hydrochloride

2005-04-08

2008-10-28

Barts, Samuel A (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

Reexamination Certificate

active

07442838

ABSTRACT:
Sertraline hydrochloride polymorphic form II is conveniently prepared by adding hydrogen chloride to solution of sertraline free amine in a ketone. In preferred processes, the solution of sertraline free amine seeded with some crystals of polymorphic form II and/or the solution is heated before addition of the hydrogen chloride.

REFERENCES:
patent: 4536518 (1985-08-01), Welch, Jr. et al.
patent: 5082970 (1992-01-01), Braish
patent: 5248699 (1993-09-01), Sysko et al.
patent: 5463126 (1995-10-01), Williams
patent: 5734083 (1998-03-01), Wilson et al.
patent: 6495721 (2002-12-01), Schwartz et al.
patent: 6939992 (2005-09-01), Van Der Schaaf et al.
patent: 0928784 (1999-07-01), None
patent: 2000-26378 (2000-01-01), None
patent: 98/27050 (1998-06-01), None
patent: 99/47486 (1999-09-01), None
patent: 00/32551 (2000-06-01), None
patent: 03/093217 (2003-11-01), None
Prof. Dr. Jürgen Falbe et al., Römpp Chemie Lexikon, 10. Ed., p. 1896 (1979).
Wolfgang Beckmann et al., Organic Process Research & Development, vol. 2, No. 5, pp. 298-304 (1998).
J. B. Conant et al., Organic Syntheses, CV 1, 345.
L. G. Wade, Organic Chemistry, 2ndEd., pp. 998-1001, (1991).

Affiliated with

Also associated with

Rating

Polymorphic forms of sertraline hydrochloride does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymorphic forms of sertraline hydrochloride, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymorphic forms of sertraline hydrochloride will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3988358