Polymeric matrices and their uses in pharmaceutical compositions

Details Polymeric matrices and their uses in pharmaceutical compositions Polymeric matrices and their uses in pharmaceutical compositions

1998-09-28

2000-07-04

Krass, Frederick

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424423, 424426, 424486, 424499, 424501, 514 2, 514 8, 514 12, 514825, 514885, 514903, 518953, 518964, A61F 200, A61F 1300, A61K 914

Patent

active

060835214

ABSTRACT:
This invention provides pharmaceutical compositions comprising polymeric matrices, especially those comprising IL-6 as an active ingredient. Specific novel poly(ethylene carbomate) polymers are also provided for more general use as matrix materials in sustained release compositions containing pharmacologically active compounds, as are methods of using of IL-6 for treatment of conditions mediated by IL-1 and/or TNF.alpha., e.g., certain autoimmune and inflammatory conditions, as well as septic shock.

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