Polymeric compound, MF-300, with protective activity against bac

Details Polymeric compound, MF-300, with protective activity against bac Polymeric compound, MF-300, with protective activity against bac

1981-06-02

1982-09-28

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 168, A61K 3173, C07H 1522

Patent

active

043518303

ABSTRACT:
A new polymeric compound, MF-300, is provided, which possesses a specific protective activity against bacterial infections caused particularly by Pseudomonas aeruginosa. The compound is derived from the reaction of ribostamycin with crotonoyl chloride followed by concentration of the reaction product and by subsequent recovery therefrom of a fraction having a range of molecular weights of 10,000.about.100,000 when measured by ultrafiltration method.

REFERENCES:
patent: 4125706 (1978-11-01), Umezawa et al.
patent: 4169890 (1979-10-01), Miyazawa et al.
patent: 4170641 (1979-10-01), Akita et al.

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