Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – From carboxylic acid or derivative thereof
Patent
1990-06-12
1991-10-01
Nielsen, Earl
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
From carboxylic acid or derivative thereof
528357, C08G 6308
Patent
active
050534858
ABSTRACT:
A polymer lactide is prepared by the polymerization of meso-3,6-dimethyl-1,4-dioxane-2,5-dione or mesodilactide and, if desired, other monomers. The mesolactide monomer has preferably a free acid content of less than 1 meq/kg dilactide and is then polymerized in a manner known per se. The compositions containing polymesolactide obtained according to this process do not posess the typical characteristics of poly-DL-lactide, poly-D-lactide or poly-L-lactide. A shorter degradation time of a substrate based on the present polymer is unofficial for several purposes. The present polymers have a good biocompatibility and are thus suited for bone plates, clamps and sutures and controlled release of biologically active compounds. The present polylactides and/or copolymers thereof have the benefit of a good biodegradability, biocompatibility, non-toxicity and non-mutagenicity.
REFERENCES:
patent: 3636956 (1972-01-01), Schneider
patent: 4033938 (1957-07-01), Augurt et al.
patent: 4719246 (1988-01-01), Murdoch et al.
patent: 4743257 (1988-05-01), Tormala et al.
Chemical Abstracts 108, 56715c (1988), (Published 2-22-88).
Schindler et al., "Poly(lactate) III Stereoselective Polymerization of Meso-Dilactide", Journal Poly, Sic: Part C: Polymer Letters, 26, 47-48 (1988).
Derwent abstract of German Patent No. 1,595,085.
Mol Arie C.
Nieuwenhuis Jan
C.C.A. Biochem B.V.
Nielsen Earl
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