Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-04-05
2010-12-28
Saeed, Kamal A (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S318000, C514S326000, C514S330000, C544S129000, C546S194000, C546S208000, C546S210000, C546S214000, C546S226000
Reexamination Certificate
active
07858624
ABSTRACT:
Described are compounds which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with renin activity. Also described are methods of use of these compounds for treating or ameliorating a renin mediated disorder in a subject.
REFERENCES:
patent: WO 2006/042150 (2006-04-01), None
Dorwald F. A. Side Reactions in Organic Synthesis, 2005, Wiley: VCH, Weinheim. Preface and Chap. 1 included.
Kubinyi, ed. 3D QSAR in Drug Design: Ligand-Protein Interactions and Molecular Similarity, vol. 2-3, Springer, 1998, 800 pages (relevant portions included).
Baldwin John J.
Cacatian Salvacion
Claremon David A.
Dillard Lawrence W.
Ishchenko Alexey V.
Hamilton Brook Smith & Reynolds P.C.
Otton Alicia L
Saeed Kamal A
Vitae Pharmaceuticals, Inc.
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