Piperazinyl-imidazo[1,2-a]pyrazines

Details Piperazinyl-imidazo[1,2-a]pyrazines Piperazinyl-imidazo[1,2-a]pyrazines

1979-09-07

1980-12-30

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544346, 544350, 544358, 544382, A61K 31495, C07D40114, C07D40314

Patent

active

042423449

ABSTRACT:
Piperazinyl-imidazo[1,2-a]pyrazines, derived from reactions between halo-imidazo[1,2-a]pyrazines with piperazine derivatives, are found to be active anorexic, antidepressant, antihypertensive, analgesic, antiarrhythmic, and/or anti-smoking agents.

REFERENCES:
patent: 3594479 (1971-07-01), Maquire et al.
patent: 3973017 (1976-08-01), Anderson
patent: 4082845 (1978-04-01), Saari et al.
DePompei et al., "J. Heterocyclic Chem.", vol. 12, (1975), pp. 861-863.
Lednicer et al., The Organic Chemistry of Drug Synthesis, 1977, John Wiley and Sons, New York, pp. 277-280.
Weissberger et al., Special Topics in Heterocyclic Chem., _1977, John Wiley and Sons, New York, pp. 11-13, 23, 183-186, 211-213.

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