Piperazine derivatives, medicaments comprising these compounds,

Details Piperazine derivatives, medicaments comprising these compounds, Piperazine derivatives, medicaments comprising these compounds,

1995-12-21

1999-07-13

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544360, 544364, C07D21158, C07D40106, A61K 31445, A61K 31995

Patent

active

059227176

ABSTRACT:
The present invention relates to piperazine derivatives of the general formula ##STR1## in which R.sub.a, Y.sub.1 to Y.sub.3 and E are defined herein, tautomers thereof, stereoisomers thereof, including their mixtures, and salts thereof, and in particular physiologically tolerated salts thereof with inorganic or organic acids or bases. These compounds have valuable pharmacological properties, such as aggregation-inhibiting activity. This invention also relates to medicaments comprising these compounds and to processes for the preparation of these compounds.

REFERENCES:
patent: 4539322 (1985-09-01), Campbell et al.
patent: 4895846 (1990-01-01), Poindexter et al.

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