Pichia methanolica secretory signal

Details Pichia methanolica secretory signal Pichia methanolica secretory signal

2007-09-18

2007-09-18

Carlson, Karen Cochrane (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C530S324000, C530S300000

Reexamination Certificate

active

11670807

ABSTRACT:
NovelPichia methanolicasecretory signal polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods of using are disclosed. Methods of producing large amounts of recombinant proteins by employing DNA constructs having a polypeptide of interest preceded by a novelPichia methanolicasecretory signal sequence.

REFERENCES:
patent: 0495208 (1992-07-01), None
patent: 99/07862 (1999-02-01), None
Anonymous, “Secondary Antibodies and Conjugates,” Calbiochem Antibody Source Book, pp. 62-65, 2004, XP002315000.
Raymond et al., “Development of the Methylotrophic YeastPichia methanolicafor the Expression of the 65 Kilodalton Isoform of Human Glutamate Decarboxylase,”Yeast 14:11-23, 1998.

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