Physiologically active substances PF1092A, PF1092B and PF1092C,

Details Physiologically active substances PF1092A, PF1092B and PF1092C, Physiologically active substances PF1092A, PF1092B and PF1092C,

1997-09-09

1998-08-04

Trinh, Ba K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30777

Patent

active

057896020

ABSTRACT:
This invention provides novel physiologically active substances PF1092A, PF1092B and PF1092C, which can inhibit binding of progesterone to progesterone receptor. These substances were obtained by culturing a fungal microorganism belonging to the genus Penicillium using a medium containing ordinary nutrients for microorganisms and isolating the physiologically active substances PF1092A, PF1092B and PF1092C from the resulting culture mixture by means of solvent extraction, silica gel column chromatography, and the like. Molecular formulae of the novel physiologically active substances PF1092A, PF1092B and PF1092C are C.sub.17 H.sub.20 O.sub.5, C.sub.17 H.sub.20 O.sub.5 and C.sub.15 H.sub.18 O.sub.4, respectively.

REFERENCES:
K. Yamakawa et al., "Studies on the Terpenoids and Related Aclycyclic Compounds . . . and (+-)-Furanoligularanone", Chemical and Pharmaceutical Bulletin, 28:11:3265-3274, (1980).
I.S. Levina et al., "Relationship Between Structure and Mode of Action of 16.alpha., 17.alpha.-cycloalkanoprogesterones (pregna-D'-pentaranes)", Chemical Abstracts, 98:21:118, col. 2, (1983).

Affiliated with

Also associated with

Rating

Physiologically active substances PF1092A, PF1092B and PF1092C, does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Physiologically active substances PF1092A, PF1092B and PF1092C, , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Physiologically active substances PF1092A, PF1092B and PF1092C, will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1178687