Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1988-06-17
1990-02-27
Schain, Howard E.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530325, 530326, 514 13, 514 12, C07K 710, A61K 3702
Patent
active
049047639
ABSTRACT:
Disclosed herein is a physiologically-active peptide represented by the following general formula (I): ##STR1## wherein X means H or H-Asp-Ser-Gly- and Y denotes -Asn-Val-Leu-Arg-Arg-Tyr-OH, -Asn-Val-Leu-Arg-Arg-OH, -Asn-Val-Leu-Arg-Tyr-OH, -Asn-Val-Leu-Arg-OH, -Asn-Val-Leu-OH or -Asn-Ser-Phe-Arg-Tyr-OH, or a salt thereof.
REFERENCES:
"Antidipsogenic Action of a Novel Peptide, `Brain Natriuretic Peptide` in Rats", Itoh et al., Eur. J. Pharm., 150 (1988), 193-196.
"Brain Natriuretic Factor", Song and Kohse and Murad, FEBS Letters, vol. 232 (No. 1), (May 1988), 125-129.
"A New Natriuretic Peptide in Porcine Brain", Sudoh et al., Nature, 332, (1988), 78-81.
"Atrial Natriuretic Peptide in the Brain: Implication of Central Cardiovascular Control", Nakao et al., J. of Hypertension, 4 (6), (1986), S492.
Tanaka et al., Biochem. Biophys. Res. Commun., 124 (2), (1984), pp. 663-668.
Lazure et al., Febs, 172 (1), (1984), pp. 80-86.
Forssmann et al., Anat. Embryol, 168, (1983), pp. 307-313.
Forssmann et al., Cell Tissue Res., 238, (1984), 425-430.
Review Article, Flynn et al., Biochem, 232, (1985), pp. 313-321.
Shiono et al., Biochem. Biophys. Res. Commun., 135 (3), (1986), pp. 728-734.
Isogai Mitsutaka
Izumi Atsushi
Kangawa Kenji
Matsuo Hisayuki
Minamino Naoto
Daiichi Pure Chemicals Co. Ltd.
Hisayuki Matsuo
Perkins Susan
Schain Howard E.
LandOfFree
Physiologically-active novel peptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Physiologically-active novel peptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Physiologically-active novel peptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-174989