Photoresponsive liposome

Details Photoresponsive liposome Photoresponsive liposome

1992-04-24

1992-12-08

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 424417, 424420, 436829, 4284022, A61K 3147

Patent

active

051696355

ABSTRACT:
A photoresponsive liposome which comprises a compound represented by the following general formula (I): ##STR1## wherein R.sub.1 is an alkyl group; R.sub.2, R.sub.3, R.sub.4 and R.sub.5, which may be the same or different, are selected from the group consisting of an alkyl group, a substituted alkyl group, an alkoxy group, a substituted alkoxy group, a halogen atom and a hydrogen atom; R.sub.6 and R.sub.7, which may be the same or different, are an alkyl group or a hydrogen atom; n is an integer of 1 to 2; and X represents a hydrophilic group, a hydrophobic group or a combination of hydrophilic and hydrophobic groups, bonded through a connecting group, provided that any of these hydrophilic and hydrophobic groups has such properties that the compound represented by the general formula (I) becomes available as a component forming the membrane of liposome.

REFERENCES:
patent: 4193983 (1980-03-01), Ullman et al.
patent: 4625014 (1986-11-01), Senter
patent: 4882165 (1989-11-01), Hunt et al.
Chem. Abs. 72:110546b (1970) Clark et al. Photoinitiated Hydrolysis of 3,5 Dimethoxybenzyl Dihydrogen Phosphates.

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