Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-06-29
1993-10-26
Tsang, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514214, 514299, 514413, 540585, 540477, 546112, 546133, 546137, 548453, 548406, A61K 31435, C07D45302
Patent
active
052566714
ABSTRACT:
Compounds of formula (I), and salts and prodrugs thereof: ##STR1## wherein Q is the residue of an optionally substituted azabicyclic ring system;
REFERENCES:
Otsuka, et al., "Role Of Substance P As A Sensory Transmitter In Spinal Cord and Sympathetic Ganglia" 1982 Substance P in the Nervous System, CIBA Foundation Symposium 91, pp. 13-34.
TIPS, (Dec. 1987) 8, pp. 506-510.
B. E. B. Sandberg, et al., J. Med. Chem. 1982, 25, 1009.
Levine, et al. Science, 1984 226, pp. 547-549.
Mantyh, et al., Neuroscience, 1988 25 (3) pp. 817-837.
D. Regoli, "Trends in Cluster Headache" Ed. Sicuteri, et al Elsevier Scientific Publishers 1987 p. 85.
Kidd, et al., The Lancet, Nov. 11, 1989 "A Neurogenic Mechanism For Symmetrical Arthritis".
Gronblad, et al., "Neuropeptides In Synovium of Patients With Rheumatoid Arthritis & Osteoarthritis" J. Rheumatol 1988 15 (12) pp. 1807-1810.
O'Byrne, et al. Arthritis and Rheumatism 1990, 33, pp. 1023-1028.
Hamlet, et al. Can. J. Pharmacol. Physiol. 1988, 66, pp. 1361-1367.
Lotz, et al., Science 1988, 241, pp. 1218-1221.
Kimball, et al., J. Immunol. 1988, 141 (10) pp. 3564-3569.
Mantyh, et al. PNAS 1988, 85, pp. 3235-3239.
Yanker, et al. Science, 1990 350 pp. 279-282.
Ladduwahetty Tamara
Swain Christopher J.
Caruso Charles M.
DiPrima Joseph F.
Merck Sharp & Dohme Limited
North Robert J.
Tsang Cecilia
LandOfFree
Azabicyclic compounds, pharmaceutical compositions containing th does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Azabicyclic compounds, pharmaceutical compositions containing th, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Azabicyclic compounds, pharmaceutical compositions containing th will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-959616