Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
2009-03-16
2011-11-22
Kosar, Andrew D (Department: 1622)
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
Reexamination Certificate
active
08063209
ABSTRACT:
Cidofovir or foscarnet based compounds having an amino acid or dipeptide esters are provided as prodrugs.
REFERENCES:
patent: 7511051 (2009-03-01), McKenna et al.
Smith, M. B. Organic Synthesis, McGraw-Hill, Inc. 1994, Chapter 1.
Liekens, et al., The Nucleotide Analog Cidofovir Suppresses Basic Fibroblast Growth Factor (FGF2) Expression and Signaling and Induces Apoptosis in FGF2-Overexpressing Endothelial Cells, Molecular Pharmacology, vol. 71, No. 3, 695-703 (2007).
Hilfinger John
Kashemirov Boris A.
McKenna Charles E.
Peterson Larryn
Pham Chi
Gifford Krass Sprinkle Anderson & Citkowski P.C.
Kosar Andrew D
Leeser Erich A
National Institute of Health (NIH)
The United States of America as represented by the Department of
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