Phosphonium salts

Details Phosphonium salts Phosphonium salts

1980-08-06

1981-10-27

Raymond, Richard

Harness for working animal

260333, 2603451, 2603452, 2603459R, 26034611, 26034622, 2603478, 424203, C07F 954

Patent

active

042974879

ABSTRACT:
Phosphonium salts represented by the formula ##STR1## wherein: R is selected from the group consisting of lower alkyl, phenyl, substituted phenyl, benzyl and substituted benzyl; R.sub.1 is hydrogen or lower alkyl; R.sub.2 is hydrogen or loweralkyl; or R.sub.1 and R.sub.2 taken together form a 5 or 6 membered saturated or unsaturated carbocyclic ring with the limitation that R.sub.1 is on the carbon atom adjacent the carbon atom bearing R.sub.2, m is 1,2 or 3; n is 0 or 1; o is 0 or 1; p is 0 or 1; R.sub.3, R.sub.4 and R.sub.5 are the same or different members of the group consisting of hydrogen, lower alkyl, lower alkoxy and halo; R.sub.6 is hydrogen or C.sub.1 --C.sub.3 straight or branched chain alkyl; and X is a pharmaceutically acceptable anion. Compounds wherein R is phenyl, substituted phenyl, benzyl or substituted benzyl are narcotic antagonists. Compounds wherein R.sub.1 and R.sub.2 are hydrogen or lower alkyl when R is lower alkyl are mixed agonist/antagonist analgesic agents and compounds where R.sub.1 and R.sub.2 taken together form a carbocyclic ring are analgesic agents.

REFERENCES:
patent: 4075407 (1978-02-01), Mueller

Affiliated with

Also associated with

Rating

Phosphonium salts does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phosphonium salts, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phosphonium salts will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-280313