Phospholipids including long-chain polyunsaturated fatty...

Organic compounds -- part of the class 532-570 series – Organic compounds – Fatty compounds having an acid moiety which contains the...

Reexamination Certificate

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C554S078000, C554S080000, C426S648000, C426S662000

Reexamination Certificate

active

07847113

ABSTRACT:
The present invention provides a method of efficiently and stably producing LCPUFA-PL. Specifically, the invention provides a method for producing phospholipids that contain LCPUFA as a constituent (LCPUFA-PL), wherein lipid producing cells producing lipids that contain long-chain polyunsaturated fatty acids (LCPUFA) are used as a starting material, the method including a PL extracting step of extracting phospholipids (PL) from defatted cells obtained by extracting triglyceride (TG)-containing oil or fat from the lipid producing cells.

REFERENCES:
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patent: 2000-245492 (2000-09-01), None
patent: 2003-048831 (2003-02-01), None
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K. Yazawa et al. “Production of Icosapentaenoic Acid From Marine Bacteria and Its Genetic Engineering.”Oil Chemistry(Abura Kagaku), 1995, vol. 44, pp. 87-93. [English Abstract & partial translation].
S. Shobou, “Oils and Fats Handbook.” 1988, p. 184. [partial translation].
G. Toffano et al., “Pharmacological Effects of Phosphatidylserine Liposomes.”Nature, 1976, vol. 260, pp. 331-333.
G. Toffano et al., “Pharmacokinetics of Radiolabelled Brain Phosphatidylserine.”Clinical Trials Journal, 1987, vol. 24, No. 1, pp. 18-24.
S. Jareonkitmongkol et al., “A Novel Δ5-Desaturase-Defective Mutant ofMortierella alpina1S-4 and Its Dihomo-γ-Linolenic Acid Productivity.”Applied and Environmental Microbiology, 1993, vol. 59, No. 12, pp. 4300-4304.
International Search Report dated Jun. 14, 2005 issued in International PCT Application No. PCT/JP2005/003344 [in Japanese].

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