Phosphatidylinositol analogues, inhibitors of phosphatidylinosit

Organic compounds -- part of the class 532-570 series – Organic compounds – Fatty compounds having an acid moiety which contains the...

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554154, C07F 902

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active

053528107

ABSTRACT:
Phosphatidylinositol analogues, inhibitors of phosphatidylinositol-specific phospholipase C of general formula (I) ##STR1## wherein X and R have the meanings specified in the description, suitable for preparing pharmaceutical compositions for the treatment of tumoral, thrombotic and inflammatory type pathologies.

REFERENCES:
Hendrickson et al., Bioorganic & Medicinal Chemistry Letters, vol. #11, pp. 615-618, 1991.
Word et al., Tetrahedron Letters, vol. 29, #46, pp. 6013-6016, 1988.

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