Phenylamidine and phenylguanidine derivatives and their use as a

Details Phenylamidine and phenylguanidine derivatives and their use as a Phenylamidine and phenylguanidine derivatives and their use as a

1993-01-27

1994-12-13

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514212, 5142282, 5142318, 5142352, 5142355, 5142358, 514252, 514253, 514316, 514318, 514323, 514326, 514343, 514414, 514422, 540597, 540598, 540602, 544 60, 544 62, 544 86, 544111, 544121, 544129, 544141, 544143, 544357, 544360, 544372, 544373, 546191, 546194, 546200, 546208, 546264, 548465, 548523, A61K 31535, A61K 3154, C07D40110, C07D40310, C07D41310, C07D41710

Patent

active

053730089

ABSTRACT:
Compounds of formula I ##STR1## and their salts in which n=0 or 1, R.sub.1 and R.sub.2 are each aliphatic or cycloalkyl or NR.sub.1 R.sub.2 is an optionally substituted heterocyclic ring, R.sub.3 is alkyl, cycloalkyl or optionally substituted amino, R.sub.5 is an aliphatic group, R.sub.6 is H, an optionally substituted aliphatic group or a cycloalkyl group, or R.sub.3 and R.sub.5 together with the nitrogen and carbon atoms to which they are attached form an optionally substituted heterocyclic ring or R.sub.5 and R.sub.6 together with the nitrogen to which they are attached form a heterocyclic ring optionally substituted by alkyl and R.sub.7 is optionally substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkoxycarbonyl, trifluoromethyl or cyano have utility as hypoglycemic agents.

REFERENCES:
patent: 3867448 (1975-02-01), Duerr et al.
patent: 4281004 (1981-07-01), Ives

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