Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-12-15
2009-06-23
Davis, Zinna N (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S310000, C514S313000, C514S314000, C514S342000, C514S343000, C514S352000, C514S619000, C546S143000, C546S144000, C546S159000, C546S276400, C546S280400, C546S304000, C546S307000, C546S312000, C564S161000
Reexamination Certificate
active
07550481
ABSTRACT:
The present invention is directed to phenylamide and pyridylamide derivative compounds of which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
REFERENCES:
patent: 5693815 (1997-12-01), Bennett et al.
patent: 2005/0038028 (2005-02-01), Faller et al.
patent: 2006/0025459 (2006-02-01), Demont et al.
patent: 2006/0211740 (2006-09-01), Demont et al.
patent: 1 186 305 (2002-03-01), None
patent: WO 02/02512 (2002-01-01), None
patent: WO 03/027068 (2003-04-01), None
patent: WO 03/045903 (2003-06-01), None
patent: WO 03/057721 (2003-07-01), None
patent: WO 03/072535 (2003-09-01), None
patent: WO 03/106405 (2003-12-01), None
patent: WO 2004/024675 (2004-03-01), None
patent: WO 2004/043916 (2004-05-01), None
patent: WO 2004/050619 (2004-06-01), None
patent: WO 2004/062625 (2004-07-01), None
patent: WO 2004/080376 (2004-09-01), None
patent: WO 2005/004802 (2005-01-01), None
patent: WO 2005/004803 (2005-01-01), None
patent: WO 2005/005374 (2005-01-01), None
patent: WO 2005/018545 (2005-03-01), None
patent: WO 2005/032471 (2005-04-01), None
patent: WO 2005/051914 (2005-06-01), None
C. A. Coburn et al., “Identification of a Small Molecule . . . ,” J. Med. Chem., vol. 47, pp. 6117-6119 (2004).
S. J. Stachel et al., “Structure-Based Design of Potent . . . ,” J. Med. Chem., vol. 47, pp. 6447-6450 (2004).
S. J. Stachel et al., “Conformationally biased P3 amide replacements of beta-secretase inhibitors,” Bioorganic & Medicinal Chemistry Letters, vol. 16, pp. 641-644 (2006).
EP Communication in EPO Appln No. 04 814 367.1, Dec. 21, 2007.
Barrow James C.
Coburn Craig A.
Davis Jennifer R.
Nantermet Philippe G.
Selnick Harold G.
Davis Zinna N
Krovatin William
Merck & Co. , Inc.
Todaro John C.
LandOfFree
Phenylamide and pyridylamide beta-secretase inhibitors for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phenylamide and pyridylamide beta-secretase inhibitors for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenylamide and pyridylamide beta-secretase inhibitors for... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4068409