Phenylacetamide derivatives and pharmaceutical compositions ther

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514620, 549441, 564165, A61K 31165, C07C23304

Patent

active

052429440

ABSTRACT:
The present invention provides novel phenylacetamide derivatives having the following formula ##STR1## wherein: X is a hydrogen, halogen, hydroxy, nitro, amino, R.sup.1, NR.sup.1 R.sup.2, NHR.sup.1 or OR.sup.1 wherein R.sup.1 and R.sup.2 are an optionally substituted C.sub.1-8 alkyl, cycloalkyl or benzyl group, respectively; Y, which may be the same or different when p is greater than 1, is a hydrogen, halogen, methylenedioxy, hydroxy, trifluoromethyl, R.sup.3 or OR.sup.3 wherein R.sup.3 is an optionally substituted C.sub.1-8 alkyl or benzyl group;

REFERENCES:
patent: 4313958 (1982-02-01), LeHann
patent: 4424205 (1984-01-01), LaHann et al.
patent: 5045565 (1991-09-01), Gardner et al.
Yaksh et al., Science 206, 1979, pp. 481-483.
Makovec et al., Chemical Abstracts, vol. 83 (1975) 193728p.

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