Phenethylamine derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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558 61, 564353, 564354, 564363, 564364, 564365, 564381, 564382, C07C21760

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active

051985870

ABSTRACT:
Phenethylamine derivatives shown by the general formula ##STR1## wherein Ro represents a lower alkyl group; R.sub.1 represents a lower alkyl group or a lower alkoxy group; R.sub.2 represents hydrogen atom or a hydroxyl group; R.sub.3 and R.sub.4 each represents hydrogen atom or a lower alkyl group; R.sub.5 represents hydrogen atom or a lower alkoxy group; X represents oxygen atom or a methylene group; m is an integer of 1-3; and n is an integer of 0-2 and the acid addition salts thereof.
These compounds exhibit a strong .alpha.-adrenergic blocking action and are useful as an antihypertensive agent.

REFERENCES:
patent: 3954871 (1976-05-01), Buu-Hoi et al.
patent: 4048229 (1977-09-01), Colella et al.
patent: 5063246 (1991-11-01), Imai et al.

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