Pharmacologically active peptide derivatives and pharmaceutical

Details Pharmacologically active peptide derivatives and pharmaceutical Pharmacologically active peptide derivatives and pharmaceutical

1990-08-03

1993-01-26

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530331, C07K 508

Patent

active

051822652

ABSTRACT:
Peptide derivatives and their salts with pharmaceutically acceptable acids or bases, having the general formula (I), ##STR1## wherein R=--H, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 acyl, alkoxycarbonyl with C.sub.1 -C.sub.4 alkyl;

REFERENCES:
patent: 4713445 (1987-12-01), Syelke
patent: 4780528 (1988-10-01), Takemoto et al.
patent: 4784988 (1988-11-01), Bruzzese et al.
Babbitt et al, Nature, vol. 317, No. 6035, pp. 359-361, (1985).
Galpin et al, Tetrahedron, vol. 36, No. 15, pp. 2247-2253, (1980).
Rudinger, J., "Characteristics of the amino acids as . . . " pp. 1-7, Parsons, j., ed., University Park Press (1976).
Plattner et al. J. Med. Chem. 1988, 31(12):2277-2288.
Gayhoff, Atlas of Protein Sequence and Structure, 1972, vol. 5, pp. 96-99.

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