Pharmaceutically active 4-hydroxy-3-benzoyl-2-quinolone derivati

Details Pharmaceutically active 4-hydroxy-3-benzoyl-2-quinolone derivati Pharmaceutically active 4-hydroxy-3-benzoyl-2-quinolone derivati

1983-06-21

1985-07-02

Rivers, Diana G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546155, 560 21, A61K 3147, C07D21522

Patent

active

045268940

ABSTRACT:
4-Hydroxy-2-quinolone derivatives are useful for their anti-inflammatory, anti-allergenic, antitussive and expectorant activity. Pharmaceutical compositions containing said compounds and pharmaceutically acceptable salts thereof and methods of treating humans and animals are described herein.

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patent: 4476132 (1984-10-01), Goschke et al.
Tomita et al., Chemical Abstracts, vol. 46, 5044b-5045f (1952).
Vul'fson et al., Chemical Abstracts, vol. 54, 24733i (1960).
Ukita et al., Chemical Abstracts, vol. 58, 8238d (1963).
Moszew et al., Chemical Abstracts, vol. 72, 31585k (1970).
Venturella et al., Chemical Abstracts, vol. 83, 178,773f (1975).
Coppola et al., Chemical Abstracts, vol. 92, 146,570g (1980).
Morinaka et al., Eur. J. Med. Chem. 1981, 16(3), pp. 251-256 (cf. CA. 95,13710c).

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