Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1995-10-27
1997-10-21
Fay, Zohreh
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
514272, 514515, 514912, A61K 3156, A61K 31505, A61K 3121
Patent
active
056796650
ABSTRACT:
It comprises: 0.005-1.0% of trimethoprim or a pharmaceutically acceptable salt thereof: 0.01-0.3% of polymyxin or a pharmaceutically acceptable salt thereof: 0.001-5% of a steroidal or non-steroidal anti-inflammatory drug and, optionally, one or more ingredients selected from among isotonizing agents, pH buffers, viscosity modifying agents, wetting agents, chelating agents, anti-oxidants, preservatives and vehicles. The formulation has a pH between 4 and 8.5.
It is applicable in the treatment of ophthalmic and otic infections accompanied by inflammation.
REFERENCES:
"Trimethoprim-polymyxin Ophthalmic Solution Versus Chloramphenicol Ophthalmic Solution In The Treatment Of Bacterial Conjunctivitis" -(Pharmakatherqapeutika, vol. 3, No. 4, 1982).
"Efficacy Of Various Drug Regimens In Benighn Otorrhea' -- Current Therapeutic Research", vol. 37, No. 6, 1985.
Chemical Abstract 96 (4) 24803 X (1981). Hugh et al.
Biosis Abstract of Vet Med Nauki, 22 (7). 1985, pp. 40-47. Verheijden et al .
Bergamini Michael Van Wie
Borras Sanjurjo Teresa
Coll Colomer Jordi
Mas Jose Alberto Vallet
Notivol Paino Ricardo
Fay Zohreh
Laboratorios Cusi, S.A.
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