Pharmaceutical compositions for treating ulcers containing 2-ary

Details Pharmaceutical compositions for treating ulcers containing 2-ary Pharmaceutical compositions for treating ulcers containing 2-ary

1985-12-20

1987-03-31

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514253, 544236, 544350, A61K 31495, C07D48704

Patent

active

046543449

ABSTRACT:
2-Aryltetraazaindenes of the formula ##STR1## wherein --A-- is --N.dbd.CH--CN.dbd.N-- or --CH.dbd.N--N.dbd.CH--, Ar is unsubstituted phenyl or phenyl mono-, di- or tri-substituted by hydroxyl, mercapto, dialkylamino, trifluoromethyl and/or --Z--R groups, Z is --O--, --S-- or --SO-- and R is alkyl, alkenyl, alkynyl or cyanomethyl, the alkyl, alkenyl and alkynyl groups each having up to 5 C atoms, and their physiologically acceptable salts, exhibit blood pressure, myocardial contraction, and anti-ulcer activities.

REFERENCES:
patent: 4327100 (1982-04-01), Austel et al.
patent: 4477454 (1984-10-01), Jonas et al.
patent: 4575505 (1986-03-01), Jonas et al.
Kutter et al, Chem. Abst. vol 82 (1975) 4251y.

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