Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1978-11-27
1980-10-21
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 1, A61K 31735, C08B 3700
Patent
active
042294401
ABSTRACT:
KGF-C is obtained by grinding kefir grain, adding water to the ground kefir grain and heating, homogenizing the mixture and centrifuging it, adding ethanol to the obtained supernatant to obtain a precipitate, dissolving the precipitate into water, purifying the obtained liquid and freeze-drying the remaining liquid. The obtained KGF-C is soluble in water and is composed of polysaccharide as principal component and contains a very small amount of nitrogenous component, and, as sugar composition, is composed of glucose and galactose in the ratio 1:1. This KGF-C has strong antitumor action by oral administration.
REFERENCES:
patent: 3855201 (1974-12-01), Buchner et al.
patent: 3988313 (1976-10-01), Bouniot
Kooiman; "Chemical Abstracts", vol. 69, 1968, p. 44,135(b).
Hattori Tokihisa
Murofushi Mitsugu
Sasaki Kuniaki
Shiomi Michio
Takeda Keniti
Brown Johnnie R.
Fujiya Confectionery Company Limited
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