Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Reexamination Certificate
2007-03-27
2007-03-27
Krass, Frederick (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
C514S449000, C424S009200, C436S064000
Reexamination Certificate
active
10334675
ABSTRACT:
The present invention relates to the bioactivity of taxanes isolated from the leaves of Himalayan Yew treeTaxus wallichianaagainst human cancer cell lines grown in-vitro and subsequent identification of brevifoliol [1] as anticancer agent useful in the treatment of various types of cancer in humans
REFERENCES:
patent: 5407683 (1995-04-01), Shively
patent: 5475120 (1995-12-01), Rao
patent: 5919816 (1999-07-01), Hausheer et al.
patent: 6333347 (2001-12-01), Hunter et al.
patent: 6759431 (2004-07-01), Hunter et al.
patent: 2003/0144570 (2003-07-01), Hunter et al.
Kobayashi et al., Effects of Taxoids from Taxus Cuspida on Microtubule Depolymerization and Vincristine Accumulation in MDR Cells, Bioorganic & Medical Chemistry Letters, 1997, vol. 7, No. 4, pp. 393-398.
Gura, “Cancer Models: Systems for identifying New Drugs are Often Faulty”, Science, vol. 278, No. 5340, pp. 1041-1042 (1997).
Georg et al., “Semisynthesis and Biological Evaluation of Brevifoliol 13-[N-Benzoyl-(2′R, 3′S)-3′-phenylisoserinate”, Bioorganic & Medicinal Chemistry Letters, vol. 3, No. 6, pp. 1349-1350 (1993).
Chattopadhyay Sunil Kumar
Garg Ankur
Khanuja Suman Preet Singh
Mishra Raghvendra Kumar
Negi Arvind Singh
Council of Scientific and Industrial Research
Darby & Darby
Krass Frederick
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