Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-05-11
1997-07-01
Weimar, Elizabeth C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, 530326, 530327, 514 13, 514 14, 514 15, A61K 3800, C07K 1400, C07K 708, C07K 706
Patent
active
056438737
ABSTRACT:
Disclosed are peptides and peptide mimetics that bind selectins, including endothelial leukocyte adhesion molecule 1 (ELAM-1). Such peptides and peptide mimetics are useful in methods for blocking adhesion of leukocytes to the selectins for the purpose of inhibiting inflammation as well as in diagnostic methods employing labeled peptides and peptide mimetics that bind selectins for the purpose of determining the site of inflammation in mammals which inflammation is mediated by the presence of one or more selectins.
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Barrett Ronald W.
Cwirla Steven E.
Dower William J.
Koller Kerry J.
Lee Jung
Affymax Technologies N.V.
Marshall S. G.
Weimar Elizabeth C.
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