Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-01-16
2007-01-16
Russel, Jeffrey Edwin (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C424S093700, C424S423000, C514S002600, C514S012200, C530S300000, C530S328000, C530S329000, C623S023570, C623S023600
Reexamination Certificate
active
10674516
ABSTRACT:
The present invention provides a composition including an isolated or recombinant peptide component that has osteogenic cell proliferative activity. The peptide, which promotes proliferation of osteoblasts, is useful for treatment of fractures, as a filler in deficient sites of bone, for inhibition of decrease in bone substance related to osteoporosis and periodontic diseases, and for prevention of fractures associated with osteoporosis and rheumatoid arthritis. The peptide, or cells that have been genetically engineered to produce the peptide, can be combined with a bone-compatible matrix to facilitate slow release of the peptide to a treatment site and/or provide a structure for developing bone.
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Dhanaraj Sridevi
Gosiewska Anna
Heavner George A.
Lin Xuanhan
Rezania Ali
Ethicon Inc.
Hoffmann & Baron , LLP
Russel Jeffrey Edwin
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