Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-04-11
2006-04-11
Gupta, Anish (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S015800, C530S328000, C530S350000
Reexamination Certificate
active
07026282
ABSTRACT:
A novel set of inhibitors of the binding interaction between human urokinase plasminogen activator (uPA) and its cell surface receptor (uPAR) has been developed. The inhibitors comprise of peptide fragments, monomeric or in multiple copies attached to a common scaffold, in which the amino acid sequence may include uncommon substituted amino acids to partially comprise of peptoid sequences. The present invention also relates to the use of such peptides in therapy, in particular for the treatment of cancer, having developed a modified non-human mammalian receptor to which the novel inhibitors are antagonistic.
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Danø Keld
Holm Arne
Holst-Hansen Claus
Ploug Michael
Stephens Ross
Cancerforskningsfonden AF 1989 (Fonden Til Fremme AF Exsperiment
Cooper Iver P.
Gupta Anish
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