Peptide and renin inhibitors

Details Peptide and renin inhibitors Peptide and renin inhibitors

1987-11-27

1993-06-01

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 530330, 530331, 530800, A61K 3700, A61K 3702

Patent

active

052159663

ABSTRACT:
Novel amino acid derivatives of the formula I

REFERENCES:
patent: 4725580 (1988-02-01), Wagnon et al.
patent: 4746643 (1988-05-01), Wagnon et al.
patent: 4755592 (1988-07-01), Raddatz et al.
Burger. Medicinal Chemistry. 1960, pp. 565-571, 578-581, 600-601.
Denkewalter et al. Progress In Drug Research. 1966, vol. 10, pp. 610-612.
Plattner et al. J. Med. Chem. 1988. 31(12). pp. 2277-2288.
Kokubu et al., Biochemical Pharmacology, vol. 22 pp. 3217-3223 (1973).
Giorgio Bolis et al., "Renin Inhibitors. Dipeptide Analogues of Angiotensinogen Incorporating Transistion-State, Nonpeptidic Replacements at the Scissile Bond"/J. Med. Chem. 1987m 30, 1729-1737.
Medicinal Chemistry, 3rd Ed. Part II. by Alfred Burger; Copyright 1970 by John Wiley & Sons.

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