Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing
Reexamination Certificate
2005-10-21
2011-12-20
Li, Bao Qun (Department: 1648)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
C424S233100, C435S320100
Reexamination Certificate
active
08080240
ABSTRACT:
According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursers, while leaving healthy cells intact. The invention thus comprises a method of killing cancer and other neoplastic and preneoplastic cells by administration of AAV2 virus, viral particles, products or replication incompetent vectors derived there from to said cells, and pharmaceutical compositions comprising the same.
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Alam Samina
Meyers Craig M.
Li Bao Qun
McKee Voorhees & Sease, P.L.C.
The Penn State Research Foundation
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