Parasitic helminth larval thiol specific antioxidant proteins an

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 234, 536 243, 536 235, 536 2433, 435 691, 435 701, 4351723, 435 692, 4353201, 4352523, 4352402, 530412, C07H 2104, C12N 1500, C12N 1536, C12P 2102

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057445931

ABSTRACT:
The present invention relates to parasitic helminth thiol specific antioxidant (TSA) larval proteins; to parasitic helminth larval TSA nucleic acid molecules, including those that encode such TSA proteins; to antibodies raised against such TSA proteins; and to compounds that inhibit parasitic helminth larval TSA activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.

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