Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1992-07-30
1993-12-28
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Dentifrices
424 52, 424 57, 424 58, 206277, 2065241, 2065243, 222107, 514718, 514721, 514900, 514901, 514902, A61K 716, A61K 718, A61K 726
Patent
active
052737411
ABSTRACT:
An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container or bottle which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. Also described is a method for inhibiting development of plaque on teeth.
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patent: 4022880 (1977-05-01), Vinson et al.
patent: 4510127 (1985-04-01), Chang
patent: 4595613 (1986-06-01), Tavss et al.
patent: 4716034 (1987-12-01), Schelm
patent: 4830221 (1989-05-01), Mazzanobile
Collins Michael A.
Gaftar Abdul
Miller Jeffrey
Potini Chimpiramma
Robinson Richard S.
Colgate-Palmolive Company
Grill Murray M.
Page Thurman K.
Spear James M.
Stone Robert L.
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