p-Nitrophenyl 2-acetylamino-4-O-(2-amino-2-deoxy-.beta.-D-glucop

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 172, 536 185, 536 41, 536179, C07H 1504, C07H 1510, C07H 1500

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active

059945206

ABSTRACT:
Disclosed is p-nitrophenyl 2-acetylamino-4-O-(2-amino-2-deoxy-.beta.-D-glucopyranosyl)-2-deoxy-.beta. -D-glucopyranoside of formula (1) and its acid-addition salts. ##STR1## The compound of formula (1) is produced by reacting a p-nitrophenyl derivative of chitin dimer with a microorganism-derived deacetylase. The compound and its salts do not act on exo-type chitinases, and are specific to only endo-type ones.

REFERENCES:
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patent: 5602020 (1997-02-01), Laine et al.
Matahira et al, N-Acetylglucosaminyl Disaccharide . . . , J. Carb. Chem., 14(2), pp. 214-217, 1995.
Tokuyasu et al., "Deacetylation of chitin oligosaccharides of dp 2-4 by chitin deacetylase from Colletotrichum Lindemuthianum", Carbohydrate Research 303 (1997) pp. 353-358.
Tokuyasu et al., "Purification and Characterization of Extracellular Chitin Deacetylase from Colletotrichum Lindemuthianum", Biosci. Biotech. Biochem. 60 (10), pp. 1598-1603 (1996).
Mitsutomi et al., "Action Pattern of Aeromonas hydrophila Chitinase on Partially N-Acetylated Chitosan", Agric. Biol. Chem. 54 (4), pp. 871-877 (1990).
K. Tokuyasu et al., "Preparation of Chitosan-related Compounds by Using Enzymatic Deacetylation Method", Chitin and Chitosan Research, 3, No. 2, pp. 142-143 (1997).
John et al., "Rhizobium NodB Protein Involved in Nodulation Signal Synthesis is a Chitooligosaccharide Deacetylase", Proc. Natl. Acad. Sci., 90, 625-629 (1993).

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