Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1999-07-27
2000-08-29
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 82, 546 83, 546 84, A61K 3144, C07D47102, C07D48702, C07D51302, C07D51702
Patent
active
061109290
ABSTRACT:
Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.
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Gerster John F.
Lindstrom Kyle J.
Marszalek Gregory J.
Merrill Bryon A.
Mickelson John W.
3M Innovative Properties Company
Desai Rita
Howard MarySusan
Ringsred Ted K.
Rotman Alan L.
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