Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-07-15
1990-11-13
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546209, 514326, 514330, 514331, A61K 31445, C07D40106
Patent
active
049702173
ABSTRACT:
Novel oxazolidinones of the formula I ##STR1## Z is O or S, R.sup.1 and R.sup.2 are each phenyl or benzyl radicals which are unsubstituted or mono- or disubstituted by alkyl, alkoxy, alkylthio, alkylsulfinyl and/or alkylsulfonyl having each 1-4 C atoms, alkanoyloxy and/or alkanoylamino having each 1-6 C atoms, F, Cl, Br, OH and/or CF.sub.3 or are heteroaryl radicals containing 1-4 heteroatoms and R.sup.3 and R.sup.4 are each H, alkyl or alkoxy having each 1-4 C atoms or are F, Cl, Br, OH or CF.sub.3, and also their salts have effects on the central nervous system, in particular neuroleptic effects.
REFERENCES:
patent: 3457267 (1969-07-01), Lunsford et al.
patent: 3821234 (1974-06-01), Koppe et al.
patent: 3856962 (1974-12-01), Alphin et al.
Chemical Abstracts 73:25438u (1970), Abstract of German Patent 1,951,273 (5/6/70).
Duncan et al., "Aroylpiperidines and Pyrrolidines, A New Class of Potent Central Nervous System Depressants", J. Med. Chem., vol. 13, No. 1, pp. 1-6, (Jan. 1970).
Bottcher Henning
Gottschlich Rudolf
Haase Anton
Minck Klaus-Otto
Prucher Helmut
Hollrah Glennon H.
Merck Patent Gesellschaft mit beschrankter Haftung
Russell Mark W.
LandOfFree
Oxazolidinones does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oxazolidinones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxazolidinones will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-777090